1. Product Identification

• Product Name: Tirzepatide
• Synonym: LY3298176
• CAS: 2023788-19-2
• Molecular Formula: C₂₂₅H₃₄₈N₄₈O₆₈
• Molecular Weight: 4813.45 g/mol

2. Physical and Chemical Properties

• Appearance: White to off-white lyophilized powder
• Purity (HPLC): ≥99.0%
• pH: 5.0–7.0 (1% solution)
• Water Content: ≤5.0%
• Solubility: Soluble in water and aqueous buffers

3. Quality Control

• Assay: 98.0%–102.0%
• Single Impurity: ≤0.5%
• Total Impurities: ≤2.0%
• Heavy Metals: ≤10 ppm
• Endotoxins: ≤10 EU/mg

4. Storage & Stability

• Storage: -20 °C, sealed, dry, protected from light
• Stability: Stable for 24 months under recommended storage
• Avoid repeated freeze-thaw cycles

5. Application